Pharmaceutical Grade Hydroxypropyl-Beta-Cyclodextrin with High Reputation CAS 128446-35-5

Basic info.

CAS No.: 128446-35-5

Other Names: 2-HP-BETA-CD,2hpbcd

MF: :C42H70-nO35(C3H8O2)n

Type: Auxiliaries and Other Medicinal Chemicals, Pharmaceutical intermediates

Grade Standard: Cosmetic Grade, Food Grade, Medicine Grade, pharmaceutical grade

Purity: >99%

Appearance:white,powder,sweet,inodorous,nontoxic

Quality standard: EP8.0, USP38, CP2015, Enterprise standard

Shelf life: 24 months

molecular weight: 1134.98+58n

Sample: free of charge

Standard: USP38,EP8.0,CP2015

MOQ: 1KG

Analysis: All detected by ourselves

Technical Service: Approved

Description:

Hydroxypropyl-β-cyclodextrin(HP-β-CD) is the hydroxyalkylated derivatives of β-cyclodectrin(β-CD).HP-β-CD is non-toxic and has no side effect,and it can significantly improve the solubility of insoluble drugs to dissolve insoluble or poorly water-soluble drugs due to its structural particularity.Therefore,it can effectively increase bioavailability of drugs;it can also improve drug quality and variety of the properties,preparation technology,stability,pharmacology,toxicology,teratogenic,mutagenic,carcinogenic,hemolysis,irritation and other aspects of HP-β-CD have already been performed;the safety of this drug has been evaluated accurately.Among all the derivatives of β-CD,HP-β-CD is considered as a type of pharmaceutical excipients with most complete research data and highest medicinal value,and it has been studied in-width and in-depth with most complete research data and highest medicinal value,and it has been studied in-width and in-depth mostly.

Applications: 

Hydroxypropyl-β -cyclodextrin (HP-β -CD) is one of the most widely used cyclodextrin derivatives in current scientific researches and industry applications. It mainly used in food, pharmaceutical and cosmetics industries. 

1. In pharmaceuticals industry, HP-β -CD can increase solubility and bioavailability of insoluble drugs, so that the efficacy of drugs can last longer with less ingestion of drugs. It can adjust and control drugs release ratio, decrease side effects of drugs, and enhance stability of drugs. HP-β -CD can be used for oral medication, injection, mucosal delivery systems (including the nasal mucosa, rectum, cornea, etc. ), dermal drug delivery systems, lipophilic drugs targeting delivery, and also used as protective agent and stabilizer of protein. 

2. In food and perfume industry, HP-β -CD can enhance the stability of nutritional constituent and extend active time of effective constituent. It can cover up bad smell and bad taste of nutritional constituent. It also can improve production processes and product quality. 

3. In cosmetics industry, HP-β -CD can reduce stimulate of organic molecular in cosmetic to the skin and mucosa. It can enhance the stability of matter, by preventing oxidation and volatilization of nutrients