Minoxidil to Reduce Hair Loss and Increase Hair Growth CAS: 38304-91-5

Basic info.

Minoxidil

CAS: 38304-91-5

Molecular Weight: 209.2483

Formula: C9H15N5O

Melting point : 258-262

Content : ≥ 99%

Specifications: 25KG / drum

Properties: The product is white or almost white crystalline powder. Dissolved in glacial acetic acid , slightly soluble in ethanol , slightly soluble in chloroform or water , very slightly soluble in acetone.

Description:

Minoxidil is a clinical oral medication for lowering blood pressure, also known as minoxidil, piperazine pyrimidine diamine, buck fixed, Minoxidil blood given, are potassium channel opener, can direct relaxation of vascular smooth muscle, there is a strong expansion of the role of small arteries, the peripheral resistance decreased, blood vessels expand, blood pressure, and had no effect on the capacitance vessels, it can promote venous return. Meanwhile, the reflex regulation and positive frequency effect, can increase cardiac output and heart rate, but does not cause orthostatic hypotension. Clinic for refractory hypertension and renal hypertension treatment. Can also be used for other antihypertensive drugs ineffective severe hypertension, but the need to avoid sodium retention diuretics and β -blockers can be combined to make increased efficacy, adverse reactions decreased.

Application:

Minoxidil was the first drug approved by the FDA for the treatment of androgenetic alopecia (hair loss). Before that, minoxidil had been used as vasodilator drug prescribed as oral tablet to treat high blood pressure, with side effects that included hair growth and reversal of male baldness.The popularity hair loss treatment is due to the general preference in the overall population for the cosmetic appearance of a full head of hair. Minoxidil is used to stimulate hair growth in areas of the scalp that have stopped growing hair. Before using topical minoxidil, the hair and scalp should be clean and dry before the minoxidil solution is applied.

Minoxidil is generally well tolerated, applied topically, is widely used for the treatment of hair loss. It is effective in helping promote hair growth in both males and females with androgenic alopecia. Minoxidil needs to be applied twice daily, and may be used indefinitely for continued support of existing hair follicles and the maintenance of any experienced hair regrowth. To achieve maximum effect, the solution should be in contact with the scalp for at least 4 hours before allowing hair to get wet.Minoxidil stimulates hair follicles and growth, but does not reduce dihydrotestosterone (DHT) or the enzyme responsible for its accumulation around the hair follicle, 5-alpha reductase, which is the primary mediator of male pattern baldness in genetically susceptible individuals.[35] Therefore, when treatment is stopped, the DHT has its expected effect of shrinking and ultimately destroying the genetically predisposed hair follicles. There are multiple types of minoxidil applications: dropper, foam and spray.