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Analgesic Antipyretic / Phenacetins Pharmaceutical Intermediates
Analgesic Antipyretic / Phenacetins Pharmaceutical Intermediates
  • >= 10  Kilogram US $50.000
Supply Ability:
5000 Kilogram/Kilograms per Month
Port:
Guangzhou
Email:
Quantity:
Kilogram
  • Product Detils
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Quick Details
Place of Origin:
China (Mainland)
Brand Name:
Kafen
Model Number:
200-533-0
Packaging & Delivery
According to your requirements.
Product Description

Analgesic Antipyretic / Phenacetins Pharmaceutical Intermediates



Basic info.


English name: Phenacetin-Acetate

EINECS number: 200-533-0 

Molecular formula: C10H13NO2 

Molecular Weight: 179.2157 

Molecular structure:

Density: 1.099g/cm3

Melting point: 133-138 ºC 

Boiling point: 355.1 ° C at 760 mmHg 

Flash Point: 168.5 ° C 

Water-soluble: 0.076 g / 100 mL 

Vapor Pressure: 3.21E-05mmHg at 25 ° C

Assay: 100.58%

Appearance:  White crystalline powder 


Descriptions: 


Using for : reliving wound pains


Section 1st.


It is also called acetophenetidin. Having glossy leaflets or scales-like crystals that have no odor or taste. 

Melting point 134 ~ 137. Stable in air, soluble in water, slightly soluble in boiling water, slightly soluble in 

ether, soluble in ethanol, chloroform. It is formed through the etherification,reduction and Acetylation 

reaction of pchloronitrobenzene. As chloroacetanilide antipyretic and analgesic agent. Suitable for fever,headache, neuralgia and other drugs as a compound agent.


Section 2nd.


Antipyretic effect is stronger than the analgesic effect. Effect of strength is slow and long-lasting as aspirin, 

low toxicity. Research shows that: This product and its metabolites acetaminophen have the antipyretic 

effect. Because the enzyme inhibitor make phenacetin-Acetate   not be converted into paracetamol, still showed 

obvious antipyretic effect,thus the antipyretic effect after the product line not converrt to paracetamol.The 

mild phenacetin-Acetate  analgesic effect usually lasts 3 to 4 hours; and synergistic effect, of alicylic acid 

coadministrationmake the analgesic effect enhancement. The main clinical is for small animal antipyretic analgesic. This product is also a component of the APC tablet.


Setion 3rd.


Phenacetin-Acetate  is a pain-relieving and fever-reducing drug, widely used from its introduction in 1887 until banned in the US by the FDA in 1983. Its use has declined because of its adverse effects, which include increased risk of certain cancers and kidney damage. It is metabolized into paracetamol, which replaced it in some over-the-counter medications following the ban on phenacetin-Acetate.


Applications:


Analgesic, antipyretic. Component of APC tablets, analgesic mixture also containing aspirin. Phenacetin-Acetate is reasonably anticipated to be a human carcinogen; Analgesic mixtures containing Phenacetin-Acetate are listed as known human carcinogens.


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