Ethisterone CAS Registry Number 434-03-7

Basic info.

Name: Ethisterone

CAS No.: 434-03-7

Formula: C21H28O2

Molecular Weight: 312.49

EINECS: 207-096-5

Assay: >98%

Appearance: Off-white powder

Density: 1.13 g/cm3

Melting Point: 263-269 °C(lit.)

Boiling Point: 446.4 °C at 760mmHg

Flash Point: 190.2 °C

Storage: Keep it under seal in cool and dark place

Package: 1kg/foil bag or according to the customers requirements.

Description:

Ethisterone (pregneninolone, 17α-ethynyltestosterone or 19-norandrostane) is a progestin. It is the 17α-ethynyl analog of testosterone, and was synthesized in 1938 by Hans Herloff Inhoffen, Willy Logemann, Walter Hohlweg, and Arthur Serini at Schering AG in Berlin and marketed in Germany in 1939 as Proluton C and by Schering in the U.S. in 1945 as Pranone. It was the first orally-active progestin.

Ethisterone was also marketed in the U.S. from the 1950s into the 1960s under a variety of trade names by other pharmaceutical companies that had been members of the pre-World War II European hormone cartel (Ciba, Organon, Roussel).

Application:

Estrogen Replacement Therapy

In recent years, estrogen replacement therapy has been criticized for its association with breast and uterine cancer, heart disease, and strokes. Hormone replacement therapy (HRT) should be used only in extreme cases and always under the supervision of a healthcare professional.