Basic Info
Cas No.: 38234-21-8
Molecular Formula: C55H76N16O12
Molecular Weight: 1153.26
Purity (HPLC): 99.0%
Appearance: White powder
Single Impurity (HPLC): 1.0%
Amino Acid Composition: 10% of theoretical
Peptide Content (N%): 80% (by %N)
Water Content (Karl Fischer): 6.0%
Acetate Content (HPIC): 15.0%
MS(ESI): N/A
Mass Balance: 95.0~105.0%
Customized: Non-Customized
Suitable for: Elderly, Adult
Purity: >99%

Product Introduction:

Fertirelin is a synthetic luteinizing hormone-releasing hormone (LH-RH) analogue, and it is a potent LHRH agonist. After a transient increase, continuous administration results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.

Fertirelin was administered at the beginning of the protocol followed 7 days later by 500 μ G cloprosterol. Two days later, a second dose of fertirelin was given and AI performed 16-19 h later regardless of the incidence of behavioral oestrus. The conception rate did not differ between the 50 μ G fertirelin group (61.1%; N = 72) and the 100 μ G group.

Product Application:

Mainly has a strong angiotensin II vasoconstriction and increase in blood pressure. The mechanism is: 1. So that the body arteriole smooth muscle contraction, increased peripheral resistance; 2. So increase the release of adrenal aldosterone, causing sodium retention, increased blood volume; 3. Directly contribute to renal tubular sodium and water reabsorption; 4. So the brain central nervous sympathetic vasoconstrictor activity, causing increased peripheral vascular resistance; 5. Stimulate the adrenal medulla to release epinephrine and norepinephrine

An endogenous antidiuretic hormone in most mammalian species. It is released into the blood from nerve terminals in the posterior pituitary and median eminence. It is a neurotransmitter in the central nervous system and also implicated in a variety of physiological processes such as regulating water balance by antidiuretic action. It is a peptidic V1a receptor agonist that produces vasoconstrictio n via V1aR-mediated vascular smooth muscle cell contraction and is being used to increase blood pressure in septic shock, a form of vasodilatory hypotension.

Fertirelin Acetate ----Indications

· To supplement LH in cases of ovulation failure.
· To induce lactation post partum.
· Management of genital hypoplasia and reduced libido in males.
· To manange signs of estrus in ferrets.