Nonapeptide-1 Details
CAS NO.: 868844-74-0
MW: 1075.16nonapeptide-1 MF: C61H87N15O9S
Standard: Cosmetic standard
Reference: Melanostatine-5, Melanostatine
Sequence (Three-Letter Code): Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val
Useage: Skin whitening
Appearance: White Crystalline powder
Assay: 99%
Category: Pharmaceutical Raw Materials, Fine Chemicals, Bulk drug

Nonapeptide-1 Description:

Nonapeptide-1 is a skin lightening peptide, derived from the melanocyte stimulating hormone (MSH). It prevents the activity of tyrosine in the melanocytes, melanin synthesis inhibition and helps to even out your skin tone by lessening hyper-pigmentation. This process reduces the formation of unwanted pigmentation, allowing for the control over skin tone and brown spots.

Nonapeptide-1, also called Melanostatine 5, is a propriety peptide that was originally developed for its antimicrobial activities. Animal research has revealed, however, that nonapeptide-1 can inhibit the synthesis of melanin, which makes it of interest for treating certain skin conditions. Animal models suggest that nonapeptide-1 can reduce synthesis of melanin and help decrease skin pigmentation to a substantial degree.

Nonapeptide-1 is a skin lightening peptide, derived from the melanocyte stimulating hormone (MSH). It prevents the activity of tyrosine in the melanocytes, melanin synthesis inhibition and helps to even out your skin tone by lessening hyper-pigmentation. This process reduces the formation of unwanted pigmentation, allowing for the control over skin tone and brown spots.

Nonapeptide-1 Application:

Nonapeptide-1 is of primary research interest for its ability to reduce hyperpigmentation by inhibiting the action of tyrosinase in melanin-producing cells. The ability to regulate melanin production has potential application in a number of conditions, including photodamage of the skin.

Research also suggests that nonapeptide-1 may play a role in the central nervous system where it may act on both dopaminergic receptors and opioid receptors to modify pain signaling as well as behavior. Studies in mice support the idea that nonapeptide-1 may have central actions that affect behavior and pain .

Nonapeptide-1 Fuction:

In cosmeceutical terms, nonapeptide-1 is a radiance promoter and whitening agentv. In technical terms it is a melanin synthesis inhibitor that works by interfering with the action of tyrosinase. Tyrosinase is the primary enzyme responsible for the synthesis of melanin in specialized cells called melanocytes. Any interference with tyrosinase prevent melanocytes from producing pigmentv . By inhibiting tyrosinase, nonapeptide-1 can help to reduce pigment production in the skin in animal studies and thus lighten darker areas that have been damaged by the sun and certain diseases.

Functions of nonapeptide:
1). Nonapeptide-1 Blocks the binding of α-MSH with its receptor MC1R on the cell membrane of melanocyte. The successive melanine producing process is stopped.
2). melanostatine is a whitening agent that works on the very initial stage of skin darkening mechanism. Highly efficacious.
3). melanostatine prevents further activation of tyrosinase & thus blocks melanin synthesis for better control over skin tone & brown spots.
4).nonapeptide Prevents hyperproduction of melanin.
5).nonapeptide's Whitening activity proven on Asian skin.
 

Specification: