Estrogen Steroids Diuretic Drugs White Powder Spirono-Lactone 52-01-7

Quick Details

Product Name:Spirono-Lactone

Other Name:17-Hydroxy-7-alpha-mercapto-3-oxo-17-alpha-pregn-4-ene-21-carboxylic acid-gamma-lactone-7-acetate

CAS: 52-01-7

MF: C24H32O4S

MW: 416.57

EINECS: 200-133-6

Product Categories: Active Pharmaceutical Ingredients; Biochemistry; Steroids; Steroids (Others); Intermediates & Fine Chemicals; Pharmaceuticals; API's; ALDACTONE

Chemical Properties White to Off White Solid

Package:20kg/carton or as your inquiry 

Reference FOB Price:$0.5/g

MOQ:1kg

Specification:ISO9001,USP,BP,GMP

Trade Mark:CQSP

Port:Shenzhen/Shanghai,China

Production Capacity:5000kg/month

HS code: 3101009020

More details pls contact:Whatapp:86 13048470428  

 Skype/E-mail : summer at chembj.com

Usage

It is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia

diuretic, aldosterone antagonist

It can be used as a kind of inefficient diuretic drugs. 

It is a synthetic 17-lactone steroid which is a kind of renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension and hypokalemia. 

The active metabolite of lactone (spirono-lactone); It can be used for the Inhibition of aldosterone biosynthesis. It can also be used as the blocker of the Quabain effect. 

Items Specification

Appearance almoste white crystalline powder 

Melting point 198-209°C

Specific rotation between -33°And- 37° 

Indentificaftion meet the requirements 

Relate substances sum of impurities 

(except canrenone) ≤ 1.0% 

Canrenone ≤ 1.0% 

Sum of impurities+canrenone ≤ 1.0% 

Chromium ≤ 50ppm 

Loss on drying ≤ 0.5% 

Sulphated ash ≤ 0.1% 

Heavy Metal  ≤ 0.002%   

Limit of mercapto compounds Conform 

Ordinary impurities Conform 

Assay (on the dried basis) 97%~102.0% 

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