Product name : RAD140
Alias: Testolone
CAS Number : 118237-47-0
MW : 393.826
MF : C20H16ClN5O2
Purity : 99.5%(HPLC)
Apprarance : White crystalline powder.
Usage : Gain muscle and lean mass
The recommended dosages: 20 to 30 mg per day, the optimal cycle duration is 12-14 weeks
Testolone (RAD140) is the newest compound in the family of selective androgen receptor modulators, or as they are better known – SARMS. Therefore, its major advantage over anabolic steroids is that it offers similar positive results, with barely any side effects at all. Indeed, this is quite a unique compound, even when it is compared to other SARMS, and in this article we shall review the most interesting aspects of RAD140.
RAD140 is the latest addition to the line of SARMS, where it shines with very strong anabolic properties, and extremely mild side effects. Due to this safety, RAD140 will be a perfect match in any steroid or PED stack, and it will definitely be a very beneficial compound to use with highly androgenic steroids, since it will prevent prostate enlargement. Besides, testolone has yet another advantage over most PED – it is a legal compound that can be purchased as a research chemical. All in all, testolone is an unbeatable PED today, since it will increase endurance, recovery, strength, and muscle mass.
Description of RAD140
RAD140 is a nonsteroidal selective androgen receptor modulator, or SARM, that resulted from an internal drug discovery program that began in 2005.
RAD140 is a SARM that is designed to act as if the tissues of the body are getting a good dose of testosterone without the unwanted side effects of anabolic steroids. It has been shown to enhance speed, stamina and endurance during workouts as well as increase muscular gains within shorter periods of time.
RAD140 has the unique property of countering the prostate-enlargement caused by testosterone use, which makes it a perfect stacking agent for highly androgenic steroids that can cause this undesired effect.
Furthermore, when Testolone was given to monkeys, there was a drastic increase in lean bodyweight during the administration period. This increase in lean mass was dosage dependent, so with bigger dosages there was a more pronounced increase in lean mass and loss of fat tissues. Hence, testolone is a true SARM with all the properties that are expected from compounds of this kind – safety and effectiveness.
How it Works
Just like the rest of the SARMS, testolone has a selective mode of action, which allows it to have anabolic effects without the side effects usually seen with anabolic androgenic steroids (AAS). These side effects include prostate enlargement, suppression of natural testosterone production, head hair loss, and many others. This means that RAD140 interacts almost exclusively with the androgenic receptors in the muscle tissues and bones, but it does not activate these receptors in other parts of the body. As a result, we get pronounced anabolic effects, but without side effects and suppression, which opens new possibilities for medical applications of this compound instead of testosterone. What's more, due to the selective mode of action, RAD140 is safe for females too, since it will not cause virilization, or clitoris enlargement.
Application of RAD140
RAD140 has demonstrated potent anabolic activity on muscle and bone in preclinical studies and has completed 28-day preclinical toxicology studies in both rats and monkeys. Because of its high anabolic efficacy, receptor selectivity, potent oral activity and long duration half-life, we believe that RAD140 has clinical potential in a number of indications where the increase in lean muscle mass and/or bone density is beneficial, such as treating the weight loss due to cancer cachexia, muscle frailty and osteoporosis, and also in the treatment of breast cancer.
Uses in bodybuilding
Logically, testolone can render incredible benefits to an athlete without the cost of prominent side effects seen with anabolic androgenic steroids. Particularly, testolone will drastically improve one's endurance and recovery, which will further lead to a considerable increase in muscle mass and strength. Consequently, RAD140 will be a great addition to any sort of cycle, where it will give all of these qualities without any additional side effects. Besides, it can be successfully used solo in a long cycle, since it causes no suppression.
The benefits of RAD140
Enhanced speed, stamina and endurance during high-intensity workouts
Faster buildup of muscular tissues that helps you achieve more gains in a shorter period of time
Based on medical tests, RAD 140 SARM also displayed a greater anabolic effect than testosterone when used. Researchers pointed out that besides having a more "reinforced" effect than testosterone, RAD 140 SARM was also seen to help reduce the androgenic side effects that can be potentially caused by the same on the prostate.
This makes its usage way safer and more effective compared to traditional prohormones and anabolic steroids available commercially.
RAD140 compared to testosterone
Testosterone is considered as the perfect comparison template in terms of androgenic and anabolic effects of different compounds, where a ratio of 1[00:10]0 is the baseline. In this regard, RAD140 has an impressive ratio of 90:1. This means that it is almost as anabolic as testosterone is, but it lacks the androgenic effects, which is a very positive thing, since most of the side effects associated to steroid use come from their androgenic effects.
In addition to that, it has been determined that you would need 40% more of testosterone for the same muscle growth as with RAD140, and yet it would take 60 times more of RAD140 to even start showing any prostate related side effects.
Regarding the affinity to androgen receptors, studies have shown that it has approximately 30% of the affinity seen with testosterone, and almost the same affinity as dihydrotestosterone (DHT).
Related SARMS and each Usage
Name | CAS NO. | Usage |
AICAR | 2627-69-2 | acts by entering nucleoside pools, significantly increasing levels of adenosine |
during periods of ATP breakdown | ||
MK2866 | 841205-47-8 | medical prescription for prevention of cachexia, atrophy, and sarcopenia and |
for Hormone or Testoserone Replacement Therapy. | ||
MK-677 | 15972-10-0 | A hormone secretagogue, treatment of obesity, a promising therapy |
for the treatment of frailty in the elderly | ||
LGD-4033 | 1165910-22-4 | pharmacological profile similar to that of enobosarm, Ostarine,MK-2866 |
GW1516 | 317318-70-0 | For obesity, diabetes, dyslipidemia and cardiovascular disease |
Andarine(S4) | 401900-40-0 | partial agonist, intended mainly for treatment of benign prostatic hypertrophy |
SR9009 | 1379686-30-2 | under development at The Scripps Research Institute (TSRI), |
increases the level of metabolic activity in skeletal muscles of mice | ||
RAD140 | 1182367-47-0 | New generation for gaining mass and cutting edges |
YK11 | 431579-34-9 | YK11: a SARM and myostatin inhibitor in one |
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