Peptides HGH Fragment 176 191 Injectable Human Growth Hormone AOD-9604 weight loss supplements No Side Effect CAS 221231-10-3 

Basic Info

Product Name: AOD-9604 

Customized: Customized

Suitable for: Lab Research

Purity: >99%

CAS No: 221231-10-3

MW:1815.08152

MW:C78h123n23o23s2

Transport Package: by Glass Vials

Origin: China

Color: White Lyophilized Powder

Trademark: UP-BIO

Specification: 2mg/vial 5mg/vial 10mg/vial

HS Code: 3001200020

What is AOD9604?

AOD9604 is a peptide fragment of the human growth hormone. AOD9604 has been specifically designed to have no anabolic effects It has been proven effective at the ability to stimulate lipolytic (fat burning) and anti-lipogenic activity. AOD9604 stimulates lipolysis (the breakdown or destruction of fat) and inhibits lipogenesis (prevents the transformation of fatty food materials into body fat). When APD9604 was founded, it was a research drug that could have the catabolic (fat-busting) effects of human growth hormone, without its (muscle-building) anabolic effects.

How much should I use of AOD9604?

AOD9604 can be injected or taken orally. The amount is 500mcg per bodyweight for 19 days. However, some sites do not know the exact amount of drug some people have taken because only a small amount has been used in scientific studies.

How should I store AOD9604?

AOD9604 can come in capsules or liquid form. Capsules should be stored in a cool dry place whereas the liquid should be storied in a cool environment like your fridge or freeze.

Description :

Fragment (176-191) is a fat-loss peptide derived from the GH molecule, which directly initiates lipolysis and inhibits lipogenesis, but in order to better understand this peptide, it is imperative to have at least a rudimentary understanding of its parent hormone .

GH is a polypeptide which contains an amino acid sequence that is 191 amino acids in length. Frag (176-191) was developed by isolating and modifying the specific portion of the GH molecule responsible for the hormone's lipolytic and anti-lipogenic effects.

The portion of the molecule responsible for these effects is amino acids 176-191. In every sense, Frag should primarily be considered a fat loss peptide which performs these functions through the same pathways as traditional GH, but without exposing the user to the potentially undesirable side effects which may present themselves during GH administration.

Application : 

the GH fragment 176-191 stimulates lipolysis and inhibits lipogenesis both en vivo/en vitro.

Fragment 176191 has shown no effect on growth or insulin resistance, unlike the full GH molecule. This is the newest, most powerful GH fragment on the market. Studies have shown sustained fatloss, aimed directly at adipose tissue.

It has been shown that the fat-reducing effects of GH appear to be controlled by a small analog region of the C-terminus end of the GH molecule. This region consists of amino acids 176-191, thus the name. This peptide fragment works by mimicking the way natural hGH regulates fat metabolism but without the adverse effects on blood sugar that is seen with unmodified hGH.

Usage

In laboratory tests on fat cells from rodents, pigs, dogs, and humans, the  fragment released fat specifically from obese fat cells but not from lean ones, reduced new fat accumulation in all fat cells, enhanced the burning of fat. In rodents (rats and mice), fragment reduced body fat in obese animals but, enhanced fat burning without changing food consumption or inducing growth (as it does not increase  levels) or any other unwanted  effect. Recent research has shown AOD9604 to be an extremely potent and effective fat burner. Metabolic is developing AOD-9604 for the potential treatment of obesity. Research studies have shown that AOD9604 actually acts on the reduction of excessive adipose tissues such as those in the abdominal area, increase in muscle mass, and enhances the lipid content of the body.

These segments of the synthetic peptide AOD9604 have been researched for their in vivo effects in laboratory mice musculus. Results have shown that AOD9604 have resulted to a short-period increase in blood glucose and a more sustained increase in plasma insulin, together with other fragments such as 172-191, 177-191 and 178-191. In addition, the researchers have suggested that functionality of the peptide depends not only in the informational sequence but should also have the correct physical configuration (Ng and Borstein 1978). Also, AOD9604, being a region of high accessibility to proteases and also rich in proline, have been demonstrated to affect the conformational change in the cytoplasmic domain of the band 3 of erythrocyte membrane protein by serving as the hinge for the pivoting of the two subdomains. This then suggest that such residue is significant in conformational changes be serving as sites for peripheral protein binding in some body cells (Low et al. 1984). 

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